Dr. James Thrall

Medical, Legal, and Practice
Global pioneer James Thrall reflects on 30 years in radiology
On 1 February, Dr. James Thrall stepped down as chairman of the department of radiology at Massachusetts General Hospital, ending a 30-year career as one of the leading figures in radiology. In this exclusive article, Dr. Thrall reflects on the changes he's seen over the past 30 years in medical imaging.
February 27, 2013
2013 02 27 12 24 40 238 Thrall James 70
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Cardiac MRI analysis can provide useful information on epicardial adipose tissue, infarct size, microvascular obstruction, and myocardial edema.
Cardiovascular Radiology
MRI casts light on patient outcome after heart attack
Increased volume of fat tissue around the heart tends can be associated with greater myocardial damage after a heart attack, German researchers have reported.
A smartphone is used to take an image for a 3D-printed prosthesis.
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Example case from test set with biparametric MRI data, reference segmentation, and output from AI system. The primary MRI assessment resulted in a PI-RADS 5 lesion in the left dorsal part of the peripheral zone and a PI-RADS 4 lesion in the right dorsal part of the peripheral zone (PSA of 11.6 μg/L). Targeted biopsies from both areas showed ISUP-grade 3. All images are from the same slice location, showing a part of both lesions. A T2-weighted (T2W) image. B Diffusion-weighted image with a b-value of 1,500 s/mm2. (C) Apparent diffusion coefficient map. (D) Reference segmentation with white areas representing tumor. (E) Softmax output from AI system. Inset in the lower left corner shows the detection map (cropped around the prostate) with red voxels representing softmax values of 0.99 and yellow voxels representing softmax values of 0.59. (F) T2W image with reference (D) and detection map (inset in E) overlayed, green represents areas in which both the reference and the AI output are positive (true positive voxels for AI), red only positive in reference (false-negative voxels for AI) and blue only segmented by AI (false-positive voxels for AI).
MRI
AI comes under scrutiny in Swedish prostate MRI study
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Example case from test set with biparametric MRI data, reference segmentation, and output from AI system. The primary MRI assessment resulted in a PI-RADS 5 lesion in the left dorsal part of the peripheral zone and a PI-RADS 4 lesion in the right dorsal part of the peripheral zone (PSA of 11.6 μg/L). Targeted biopsies from both areas showed ISUP-grade 3. All images are from the same slice location, showing a part of both lesions. A T2-weighted (T2W) image. B Diffusion-weighted image with a b-value of 1,500 s/mm2. (C) Apparent diffusion coefficient map. (D) Reference segmentation with white areas representing tumor. (E) Softmax output from AI system. Inset in the lower left corner shows the detection map (cropped around the prostate) with red voxels representing softmax values of 0.99 and yellow voxels representing softmax values of 0.59. (F) T2W image with reference (D) and detection map (inset in E) overlayed, green represents areas in which both the reference and the AI output are positive (true positive voxels for AI), red only positive in reference (false-negative voxels for AI) and blue only segmented by AI (false-positive voxels for AI).
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