U.K. team to conduct personalized breast screening study

Researchers from Loughborough University in Leicestershire, U.K., plan to conduct a study investigating whether personalized breast cancer screening is a better option for women between the ages of 40 and 70.

The seven-year, randomized clinical study, called My Personalized Breast Screening (MyPeBS), will include 85,000 women from Belgium, France, Israel, Italy, and the U.K. It has received 12.5 million euros in funding from the European Union's Horizon 2020 research and innovation program and consists of a consortium of 25 European, Israeli, and American institutions, according to the university.

Drs. Yan Chen and Alastair Gale of Loughborough and colleagues will compare two groups of women: One will follow the current standard European breast screening protocol of screening mammography for women between the ages of 50 and 69 every two or three years, and the other will follow a personalized risk-based screening strategy. For the risk-based group, 300 radiologists will assess each woman and make a recommendation for when she should undergo screening mammography.

Chen and Gale plan to compare study results with those of the Women Informed to Screen Depending on Measures of Risk (WISDOM) Study, led by Dr. Laura Esserman, director of the University of California, San Francisco (UCSF) Breast Care Center. The MyPeBS trial will begin in early 2019.

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