Radiopharm collaborates with Lantheus on theranostic agent

2018 04 24 20 24 4264 Isotope 400

Radiopharm Theranostics has entered a collaboration agreement with Lantheus to develop NM-01, a nanobody that can be labeled with radioisotopes to diagnose and treat tumors for theranostic applications.

NM-01 was developed using genetically engineered, camelid-derived, single-domain antibodies. Radiopharm has additionally acquired the imaging rights of NM-01 from NanoMab for the Chinese market and worldwide intellectual property rights for any therapeutic use.

Radiopharm will soon initiate a phase I therapeutic trial in Australian patients with programmed cell death ligand 1 (PD-L1) positive non-small cell lung cancer. Radiopharm and Lantheus have agreed to cross-reference each other's data to facilitate development plans for the PD-L1 assets, including the regulatory process with the U.S. Food and Drug Administration and other key regulatory agencies.

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