Pearl Toh

Molecular Imaging
MR targeting directs cancer-killing cells
Conventional cancer treatments using chemotherapy drugs can suffer from nonspecificity. New research shows MRI can direct cancer-killing cells to target sites. Not only does this technology target cancer kills, it enables anticancer agents to reach tumor sites that are normally inaccessible.
October 1, 2015
2015 10 01 12 08 55 109 2015 10 02 Medphysweb Mrt 20151001191024
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Example case from test set with biparametric MRI data, reference segmentation, and output from AI system. The primary MRI assessment resulted in a PI-RADS 5 lesion in the left dorsal part of the peripheral zone and a PI-RADS 4 lesion in the right dorsal part of the peripheral zone (PSA of 11.6 μg/L). Targeted biopsies from both areas showed ISUP-grade 3. All images are from the same slice location, showing a part of both lesions. A T2-weighted (T2W) image. B Diffusion-weighted image with a b-value of 1,500 s/mm2. (C) Apparent diffusion coefficient map. (D) Reference segmentation with white areas representing tumor. (E) Softmax output from AI system. Inset in the lower left corner shows the detection map (cropped around the prostate) with red voxels representing softmax values of 0.99 and yellow voxels representing softmax values of 0.59. (F) T2W image with reference (D) and detection map (inset in E) overlayed, green represents areas in which both the reference and the AI output are positive (true positive voxels for AI), red only positive in reference (false-negative voxels for AI) and blue only segmented by AI (false-positive voxels for AI).
MRI
AI comes under scrutiny in Swedish prostate MRI study
An AI system trained in a screening population has lower specificity than radiologists using PI-RADS v2, but considerable care is vital, researchers from Gothenburg reported in European Radiology on 8 December.
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Molecular Imaging
Molecular imaging can trigger next revolution in radiology
Color Profiles Res
Health Equity
Challenging inequity: ESR group spells out why it matters
Back Pain 400
Nuclear Medicine
PET/MRI detects ‘unknown’ generators of musculoskeletal pain
Postoperative 3D volume rendering of the fenestrated endograft reconstruction: 3D volume-rendered reconstruction obtained in Horos using the standard soft-tissue preset. The image displays the postoperative appearance of the fenestrated endograft and visceral stents, extending from the descending thoracic aorta to the iliac bifurcation, acquired during the follow-up CT angiogram one month after the procedure. The reconstruction shows patent visceral branches with well-perfused stents, absence of endoleak, and successful restoration of the previously disconnected left limb with adequate iliac perfusion.
3D Printing
Digital workflows, 3D models enhance preoperative planning
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AI comes under scrutiny in Swedish prostate MRI study
By Philip Ward
An AI system trained in a screening population has lower specificity than radiologists using PI-RADS v2, but considerable care is vital, researchers from Gothenburg reported in European Radiology on 8 December.
December 9, 2025
Example case from test set with biparametric MRI data, reference segmentation, and output from AI system. The primary MRI assessment resulted in a PI-RADS 5 lesion in the left dorsal part of the peripheral zone and a PI-RADS 4 lesion in the right dorsal part of the peripheral zone (PSA of 11.6 μg/L). Targeted biopsies from both areas showed ISUP-grade 3. All images are from the same slice location, showing a part of both lesions. A T2-weighted (T2W) image. B Diffusion-weighted image with a b-value of 1,500 s/mm2. (C) Apparent diffusion coefficient map. (D) Reference segmentation with white areas representing tumor. (E) Softmax output from AI system. Inset in the lower left corner shows the detection map (cropped around the prostate) with red voxels representing softmax values of 0.99 and yellow voxels representing softmax values of 0.59. (F) T2W image with reference (D) and detection map (inset in E) overlayed, green represents areas in which both the reference and the AI output are positive (true positive voxels for AI), red only positive in reference (false-negative voxels for AI) and blue only segmented by AI (false-positive voxels for AI).
Molecular imaging can trigger next revolution in radiology
By Amerigo Allegretto
Molecular imaging will play a key role in precision medicine, and radiology will be at the forefront in ensuring the best patient outcomes, predicts RSNA President Dr. Umar Mahmood, PhD.
December 8, 2025
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Challenging inequity: ESR group spells out why it matters
By Maryam Payne
Radiology staff must recognize how inequities in imaging affect patients from minority groups, says the ESR subcommittee on equity, diversity, and inclusivity.
December 8, 2025
Color Profiles Res
PET/MRI detects ‘unknown’ generators of musculoskeletal pain
By Will Morton
Potential pain generators were identified by increased F-18 FDG radiotracer uptake on PET and/or structural abnormalities on MRI.
December 5, 2025
Back Pain 400
Digital workflows, 3D models enhance preoperative planning
By Maryam Payne
Low-cost digital workflows using 3D printing and AI-assisted model-building can prove valuable for preoperative planning.
December 5, 2025
Postoperative 3D volume rendering of the fenestrated endograft reconstruction: 3D volume-rendered reconstruction obtained in Horos using the standard soft-tissue preset. The image displays the postoperative appearance of the fenestrated endograft and visceral stents, extending from the descending thoracic aorta to the iliac bifurcation, acquired during the follow-up CT angiogram one month after the procedure. The reconstruction shows patent visceral branches with well-perfused stents, absence of endoleak, and successful restoration of the previously disconnected left limb with adequate iliac perfusion.
Cryoablation treats early-stage breast cancer in older women
By Amerigo Allegretto
Cryoablation is effective in treating early-stage breast cancer in older women who do not undergo surgery, a team from Madrid reported at RSNA 2025.
December 4, 2025
Rsna 2025 Welcome
Stent procedure proves safe in pediatric liver transplant cases
By Will Morton
Biodegradable stents appear safe and effective for treating narrowing of the bile ducts in children after liver transplants, Italian researchers noted at RSNA 2025.
December 4, 2025
Biliary Atresia Disease Adobe Pikovit
Radiology must persevere with sustainability efforts
By Kate Madden Yee
It's crucial to reduce medical imaging's energy use and waste to mitigate the effect of global warming, warns RSNA 2025 keynote speaker Dr. Geraldine McGinty.
December 3, 2025
Sustainability Image
GE HealthCare features new MRI scanners, PCCT system
By Erik L. Ridley and Kate Madden Yee
Two new MRI scanners and a photon-counting CT (PCCT) system are among the RSNA 2025 highlights for GE HealthCare.
December 3, 2025
Ge Technology Photo
Abdominal obesity linked to heart damage
By Will Morton
Abdominal obesity appears to lead to a potentially pathological form of cardiac remodeling called concentric hypertrophy, German researchers have asserted.
December 2, 2025
2025 11 25 Belly Fat Heart Thumbnail
France gets set to shine at RSNA 2025
By Philip Ward
An abundance of Gallic charm and research excellence promise to light up McCormick Place in Chicago on Tuesday.
December 1, 2025
Patient with diffuse myocardial edema. Myocardial late gadolinium enhancement shows myocarditis caused by immune checkpoint inhibitors. Courtesy of Prof. Alexis Jacquier.
How are imaging modalities portrayed in movies?
By Amerigo Allegretto
Feature-length films often portray medical imaging in a negative light, according to an article in the European Journal of Radiology.
December 1, 2025
Movie Theater Adobe Mr Music
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